WiLO Student Chapter/CREOL Distinguished Seminar Series:
“Endoscopes for optical coherence imaging and fluorescence spectroscopy: design
and applications to cancer imaging” Jennifer K. Barton, Ph.D
Wednesday, May 6, 2015 11:00 AM to 12:30 PM
CREOL Room 103
CREOL Room 103
Following the lecture, WiLO is sponsoring an informal
question and answer session where Dr. Barton will discuss her career path and
experiences in the field of optics.
12:00-12:30
Celebrating the International Year of Light 2015
Jennifer Kehlet Barton, Ph.D.
Associate Vice President for Research, Professor,
Department of Biomedical Engineering, Electrical and Computer Engineering,
Optical Sciences, Agriculture and Biosystems Engineering, University of
Arizona.
Abstract:
Light-based methods have found widespread application for
biomedical diagnostics because of their inherent high sensitivity, high
resolution, relatively low cost, and ability to sense both structural and
biochemical characteristics. The primary disadvantage of most optical
techniques in vivo is the limited penetration depth of light.
This challenge can be offset by endoscopic delivery using small-diameter fiber
optics. Optical techniques hold the promise of directing, minimizing, or
perhaps even eliminating traditional destructive biopsy by providing diagnostic
information in a harmless manner.
I will discuss experiences building miniature endoscopes
that include two complimentary optical modalities: optical coherence tomography
and fluorescence spectroscope (FS), which provide micron-scale cross-sectional
imaging and information about the concentration and distribution of fluorescent
biomolecules, respectively. The challenges of miniaturization, wide wavelength
range, scanning, and navigation will be discussed. I will show progress on our
recent projects in mouse models (monitoring colon cancer) and humans
(least-invasive imaging of the ovary).
Biography:
Jennifer Barton received the BS and MS degrees in electrical
engineering from the University of Texas at Austin and University of California
Irvine, respectively. She worked for McDonnell Douglas (now Boeing) on the
Space Station program before returning to The University of Texas at Austin to
obtain the Ph.D. in Biomedical Engineering in 1998. She is currently Professor
of Biomedical Engineering, Electrical and Computer Engineering, Optical
Sciences, and Agriculture and Biosystems Engineering at the University of
Arizona. In 2012 she became Associate Vice President for Research, and from
July 2013 - June 2014 she served as Interim Vice President for Research.
Barton develops miniature endoscopes that combine multiple
optical imaging techniques, particularly optical coherence tomography and
fluorescence spectroscopy. She evaluates the suitability of these endoscopic
techniques for detecting early cancer development in patients and pre-clinical
models. Additionally, her research into light-tissue interaction and dynamic
optical properties of blood laid the groundwork for a novel therapeutic laser
to treat disorders of the skin’s blood vessels. She has published over 90
peer-reviewed journal papers in these research areas.
Barton previously was Assistant Director of the BIO5
Institute, a collaborative research institute dedicated to solving complex
biology-based problems affecting humanity. She served as the inaugural
Department Head of Biomedical Engineering and Chair of the BME Graduate
Interdisciplinary Program. She is a fellow of SPIE- the International Optics
Society, and a fellow of the American Institute for Medical and Biological
Engineering.
Following the lecture from 12:00-12:30, WiLO is sponsoring
an informal question and answer session where Dr. Bartonwill discuss
her career path and experiences in the field of optics.
For additional information:
Dr. Bahaa Saleh
407-882-3326
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