Seminar: "Multi-contrast Photoacoustic Microscopy: Listening to Anatomy, Function, Metabolism, and Biomarkers in Vivo", Song Hu
CREOL Room 102
Friday, March 23, 2012 11:00 AM to 12:00 PM
Optical Imaging Laboratory, Department of Biomedical Engineering, Washington University in St. Louis
Dr. Song Hu
Photoacoustic microscopy (PAM), combining focused optical excitation and ultrasonic detection, enables in vivo multi-contrast characterization of biological tissues down to the cellular level. In PAM, light absorption by endogenous biomolecules or exogenous biomarkers thermoelastically induces a local pressure rise and launches an ultrasonic wave, which propagates through the tissue and is received by an acoustic detector to form an image. This talk will focus on anatomical, functional, metabolic, and molecular PAM at various in vivo sites, including the brain, skin, and eye. The broad applications of PAM in neurology, vascular biology, oncology, and dermatology will be highlighted.