Tuesday, February 18, 2014

Seminar: "Label-free cellular imaging and tissue turbidity suppression" by Dr. Zahid Yaqoob 2.24.14/11:00am-12:00pm/ CREOL Room 102

Seminar: "Label-free cellular imaging and tissue turbidity suppression" by Dr. Zahid Yaqoob
Monday, February 24, 2014 11:00 AM to 12:00 PM
CREOL Room 102

Dr. Zahid Yaqoob
Laser Biomedical Research Center
Massachusetts Institute of Technology

Abstract:
Optical imaging and spectroscopy of biological cells and tissue can provide tremendous information that may be utilized for both diagnostic and therapeutic applications. A major challenge in optical imaging, however, is to elicit relevant information in a label-free fashion. While cells are generally transparent that leads to diminished image contrast, biological tissue is highly scattering that limits the working depth range of current optical imaging and spectroscopy modalities. Remarkably, quantitative analysis of amplitude and phase characteristics of the transmitted or backscattered light can lead to label-free structural and functional imaging in live cells. I will discuss the development of two- and three-dimensional quantitative phase microscopy and its applications including dry mass (non-aqueous content) measurements to study cell growth and division. Accurate optical field-based measurements can also be utilized to quantify and control multiple light scattering in turbid media. This topic has attracted significant interest in recent years, leading to different approaches for overcoming tissue turbidity. I will present active wavefront control via optical phase conjugation and demonstrate its efficacy in permitting high-fidelity wide-field imaging through turbid media.

Biography:
Dr. Yaqoob obtained his MS and PhD in Optics from The College of Optics and Photonics/CREOL, University of Central Florida. He received his postdoctoral training in biomedical optics at CalTech and MIT. He is currently a Research Scientist at the MIT Laser Biomedical Research Center, where his research is focused on developing innovative photonic solutions for complex problems in biological research and medical diagnosis. He is particularly interested in applying these tools to understand highly regulated physiological and pathological processes at single cell level. His research also focuses on developing strategies to harness multiple light scattering in biological tissue with the aim to improve the working depth range of current optical imaging and spectroscopy tools. He has published in more than 85 peer-reviewed journals and conference proceedings.

For additional information:
Dr. M. G. "Jim" Moharam                                                                     
Professor of Optics
407-823-6833
moharam AT creol . ucf . edu


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